Use of ultra-low-dose (≤6 mg) doxepin for treatment of insomnia in older people

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Low-dose doxepin for the treatment of insomnia: emerging data.

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Efficacy and safety of doxepin 6 mg in a four-week outpatient trial of elderly adults with chronic primary insomnia.

INTRODUCTION The efficacy and safety of doxepin (DXP), a histamine H(1) receptor antagonist, was evaluated in elderly adults with sleep maintenance insomnia. METHODS This was a randomized, double-blind, placebo-controlled outpatient trial. Elderly adults meeting DSM-IV-TR criteria for primary insomnia were randomized to four weeks of nightly treatment with either DXP 6 mg (N=130) or placebo (...

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ژورنال

عنوان ژورنال: Canadian Pharmacists Journal / Revue des Pharmaciens du Canada

سال: 2014

ISSN: 1715-1635,1913-701X

DOI: 10.1177/1715163514543856